Proteomics
Core Director: David L. Hachey, Ph.D.
The goal of the Proteomics Facility Core is to provide analytical proteomics capabilities to investigators in the Core Center. Proteomics is the study of proteomes, which are the functional complements to genomes and which comprise diverse structural and catalytically functional multiprotein machines. Because proteins are principal targets of many chemical and physical agents, proteomics approaches are essential to defining the molecular mechanisms by which environmental agents affect living systems. Analytical proteomics integrates tools for protein and peptide separations, mass spectrometry analysis, and bioinformatics to characterize proteomes and their component proteins. The Proteomics Facility Core is housed within the mass spectrometry shared facility, which houses instrumentation and resources used by several research centers at Vanderbilt, including the Core Center.